The associated symptoms in dercums disease include fatty deposits, easy bruisability, sleep disturbances, impaired memory, depression, difficulty concentrating, anxiety, rapid heartbeat, shortness of breath, diabetes, bloating, constipation, fatigue. Adiposis dolorosa, anders syndrome, dercumvitaut syndrome, lipalgia, adiposalgia, lipomatosis dolorosa of the legs, lipohypertrophy dolorosa, painful column leg, painful lipedema syndrome. When palpable lipomas exist they vary in size and firmness. Dercum, a neurologist in pennsylvania, in 1892, and bears his name. The cause and mechanism of dercums disease remains unknown. Oflynn skip to main content we use cookies to distinguish you from other users and to provide you with a better experience on our websites. Adiposis dolorosa is more than painful fat request pdf.
Adiposis dolorosa, also known as dercums disease 1 or anders disease, is a rare condition characterized by generalized obesity and fatty tumors in the adipose tissue. Perhaps this article will aid others in a diagnosis of adiposis dolorosa. Review article open access adiposis dolorosa a scientific. Pathophysiology the understanding of the mechanism and pathogenesis of adiposis dolorosa was unknown. Dercums disease adiposis dolorosa diagnosis registry. Dercums disease adiposis dolorosa is an unusual progressive syndrome of unknown etiology characterized by multiple painful lipomas that arise in adult life, most often affecting postmenopausal women who are obese. Dercums disease or adiposis dolorosatypescausessymptoms. Adiposis dolorosa most commonly appears between age of 3550 years, women are more prone to dercum disease than man, and the condition mainly affects postmenopausal woman, it is five to thirty times more common in women. Older medical literature states that the disease occurs most often in obese postmenopausal women, but can also occur in men. The national organization of rare diseases nord notes, dercum disease is a rare disorder in which there are fatty deposits which apply pressure to the nerves, resulting in weakness and pain.
Corticosteroidinduced juxtaarticular adiposis dolorosa steven s. Mar 20, 2015 posts about medical research written by cprentice1208. Get a printable copy pdf file of the complete article 558k, or click on a page image below to browse page by page. It is also known as dercum disease, ander syndrome, morbus dercum. Adiposis dolorosa ad is a rare disorder of painful nodular subcutaneous fat accompanied by fatigue, difficulty with weight loss, inflammation, increased fluid in adipose tissue lipedema and. Dercums disease, or adiposis dolorosa, is a rare entity, characterized by overweight or obesity and the appearance of multiple painful lipomas. Know the types, causes, symptoms, treatment, pathophysiology, epidemiology, prevention and prognosis of dercums disease or adiposis dolorosa. Mystery diagnosis the man with 100 lumps dercums disease aka. If you have problems viewing pdf files, download the latest version of adobe reader.
Possible causes include nervous system dysfunction, mechanical pressure on nerves, adipose. The scattered myocyte islets in the extensive adiposis andor fibrosis can form an electrical maze around the surgical suture area. A new casereport bouchra amine, fabienne leguilchard, claude laurent benhamou 6 february 2004. This is dercums disease also dercum disease or adiposis dolorosa, first identified by francis x. Dercums disease adiposis dolorosa is a rare condition characterized by progressively painful fatty deposits, usually, in menopausal women with obesity, asthenia and mental phenomena. If one is to judge from the number of cases reported in the literature, adiposis dolorosa is a rather rare disease. Dercums disease is a predominantly female disease occurring between the ages of 3550 years.
Dercums disease articleslinks part i posted on may 28, 2012 by cprentice1208 comments off on dercums disease articleslinks part i dercums disease adiposis dolorosa. Adiposis dolorosa dercum disease usually occurs in adults, and women are more commonly affected than men. This entity was first described by francis xavier dercum in 1862. Dercums disease or adiposis dolorosa abstract dercums disease dd, also called adiposis dolorosa ad, is known as a rare, chronic and progressive disorder characterized by multiple, subcutaneous painful adipose tissue masses. Although some of the lesions were tender, most were only appreciated with palpation. Intractable pain in a patient with adiposis dolorosa dercums disease was treated by iv administration of lidocaine 200 to 400 mg.
Subjects were white, nonhispanic except for 3 hispanics and 2 african americans, and mostly women 82. The subjective pain sensation was evaluated with a visual analog scale and number of words chosen, and the objective pain sensation with the mechanical pressure pain threshold. These deposits characteristically are located on the face, the nuchal and truncal areas, and episternally, as well as in the mediastinum and epicardium. Patient, a very corpulent woman, aged 35, complains of pains in different parts. We hereby report a case of type iii dercums disease in view of the rarity of this condition. Surveys of current sufferers seem to indicate that the disease causes the obesity. Adiposis dolorosa dercum, anders disease statpearls ncbi. Relief was maximum 20 minutes after the end of drug infusion. This site provides links to research published in peer. Juxtaarticular adiposis dolorosa may be defined as the localised accumulation of painful fat near joints, most commonly the knee. Interferon alfa2b induced longterm relief of pain in two patients with adiposis dolorosa and chronic hepatitis.
Approximately 250 cases have been described in the worlds literature since the original report of the condition by dercum in 1888. Dec 15, 2017 first described in 1892 by the american neurologist francis xavier dercum at jefferson medical college in philadelphia, pennsylvania, dercum disease adiposis dolorosa is an unusual progressive syndrome of unknown etiology characterized by multiple painful lipomas that arise in adult life, most often affecting obese postmenopausal women. The sleep disorder and other pains may be a part of the adiposis dolorosa rating as it is a part of the illness. Lipomas in people with dercums disease may be found in any part of the body. Adiposis dolorosa is a rare disorder affecting fatty tissue under the skin. Adiposis dolorosa pain management federal practitioner. Im a bit late getting this info on the site here due to life getting in the way, but here is a research article link titled an abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in dercums disease. Dercums disease diagnosis registry no one seems to know how many dercum diagnoses there are in the united states and other parts of the world, so we decided to start a registry that is somewhat anonymous.
Dercum disease adiposis dolorosa has been classified by the world health organization who as a distinct entity. Adiposis dolorosa dercum, anders disease updated 2018 dercums disease. Adiposis dolorosa, also known as anders disease or dercums disease, is a rare disease characterized by multiple painful lipomas that arise in adult life. Various areas of the body may swell for no apparent reason.
Traumainduced adiposis dolorosa dercums disease bmj. The tumors are normally painful and found in multiples on the extremities. A rare cause of breast pain is dercums disease, or adiposis dolorosa, a condition characterized by multiple, often painful subcutaneous. These lipomas mainly occur on the trunk, the upper arms and upper legs. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. Adiposis dolorosa is a rare disorder of multiple painful subcutaneous growths of. We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Pain was examined preoperatively and at 3 months, and 1, 2, 3, and 5 years after liposuction. Dercums disease adiposis dolorosa volume 1 issue 2 p. The pain is most commonly described by the patients as burning or aching. A rare cause of breast pain is dercums disease, or adiposis dolorosa, a condition characterized by multiple, often painful subcutaneous lipomas. The lipomas may be localised or diffuse and can occur at any location except the face and neck. Source national institutes of health nih ophanet, a consortium of european partners, currently defines a condition rare when it affects 1 person per 2,000.
These types of articles are always helpful to physicians or medical personnel unfamiliar with dd. Lipomas are the most common benign neoplasms of mesenchymal origin and may arise in any location where fat is normally present. Dercums disease adiposis dolorosa, or lipomatous dolorosa morbus dercum was first described by the american neurologist francis dercum in 1888. A forum and community offering information, a few other names used for dercums disease are adiposis dolorosa, adiposa dolorosa, lipomatosis dolorosa. This condition occurs most often in women who are overweight or obese, and signs and symptoms typically appear between ages 35 and 50. Dercums disease adiposis dolorosa, abstract among the symptoms reported by patients undergoing breast imaging, pain is one of the most common. However, in dercum disease adiposis dolorosa, a relationship exists between pain and body weight, with pain in the fatty tissue and obesity being fundamental criteria for the diagnosis of dercum. Dercums is a rare disease that causes painful, fatty growths to appear under the skin, sometimes all over the body. Consideration of special clinical varieties or syndromesgroups of cases. Adiposis dolorosa varicose veins nyc nj spider veins. It would seem that the infrequent occurrence of the disease is more apparent than real.
Possible causes ranges from tissue trauma to congenital. Dercum disease also known as adiposis dolorosa, anders syndrome and dercumvitaut syndrome is a rare condition that is characterized by multiple, painful fatty lipomas benign, fatty tumors that occur chiefly in postmenopausal, obese women of middle age. Adiposis dolorosa wikimili, the best wikipedia reader. Corticosteroidinduced juxtaarticular adiposis dolorosa. Get a printable copy pdf file of the complete article 197k, or click on a page image below to browse page by page.
Adiposis dolorosa is a condition characterized by painful folds of fatty adipose tissue or the growth of multiple benign noncancerous fatty tumors called lipomas. Adiposis dolorosa, also known as dercums disease, is characterized by painful lipomas that usually appear on the trunk and upper and lower proximal extremities. We report a 46yearold woman with a nineyear history of obesity. The tumors can be encapsulated or the fatty deposits can be diffuse. Adiposis dolorosa is chronic and tends to be progressive. Adiposis dolorosa, or dercums disease is a rare condition characterized by multiple, painful lipomas, or small benign fatty tumors. Like fibromyalgia, the diagnosis of dercum disease adiposis dolorosa is made clinically, and both diseases include symptoms of a number of associated diseases. The disease is characterized by painful fatty tumors andor fatty deposits. Files are available under licenses specified on their description page. Her systemic symptoms included generalized weakness, fatigue, memory impairment, and arthralgias. The pain may disappear without treatment but any manual therapy such as. A diposis dolorosa ad, or dercum disease, is a rare disorder that was first described in 1888 and characterized by the national organization of rare disorders nord as a chronic pain condition of the adipose tissue generally found in patients who are overweight or obese. Adiposis dolorosa ad, or dercum disease, is a rare disorder that was first described in 1888 and characterized by the national organization of rare disorders.
Adiposis dolorosa pain management dercums disease research. It would seem that the infrequent occurrence of the. Media in category adiposis dolorosa this category contains only the following file. Close this message to accept cookies or find out how to manage your cookie settings. Adiposis dolorosa is a condition characterized by painful folds of fatty adipose tissue or the growth of multiple noncancerous benign fatty tumors called lipomas. Cureus exophytic adiposis dolorosa dercums disease of. Adiposis dolorosa dercums disease dermatology advisor. This site explores the symptoms, personal stories and lack of research in the study of dercums disease, also known as adiposis dolorosa. Apr 30, 2012 we propose the minimal definition of dercums disease to be generalised overweight or obesity in combination with painful adipose tissue. The disease is characterized by inflammation of the fatty tissue, being known previously as fatty tissue rheumatism. The aim of this study was to describe ultrasound and magnetic resonance imaging mri features of adiposis dolorosa, dercums disease, and to evaluate the mri features prospectively against a large number of mri examinations. Dd mainly occurs in overweight or obese adults, mostly postmenopausal women. Here are links to possibly useful sources of information about adiposis dolorosa. The most common sites are the knees referred to as juxtaarticular adiposis dolorosa, upper thighs, back and upper arms.
This condition occurs most often in women who are overweight or obese, and signs. The trip database provides clinical publications about evidence. She 33f has graves disease and dercums, both separately causing a lot of secondary disorders like ibs and ocular migraine, and she has been living with us for 3 years now because living by herself was no longer possible. Adiposis dolorosa is rare and to our knowledge, the prevalence in the united states or worldwide has not been established. The understanding of the cause and mechanism of dercum disease remains unknown. These fatty growths form under the skin subcutaneous and feel like firm nodules and are typically. Adiposis dolorosa should be diagnosed through physical.
Adiposis dolorosa symptoms, diagnosis, treatments and causes. Adiposis dolorosa, also known as dercums disease or anders disease, is a rare condition characterized by generalized obesity and fatty tumors in the adipose tissue. Adiposis dolorosa is a syndrome of symptoms associated with fat metabolism and was first described by dercum in 1892 from a case in the wards of a philadelphia hospital. Affected individuals present with fatty growths, known as lipoma, found most commonly on the torso, upper parts of the limbs, and buttocks. Pdf adiposis dolorosa of scalp presenting with severe headache. The most common locations for painful fat and for lipomas are the extremities, the trunk, the pelvic area, and the buttocks figure 1. Adiposis dolorosa is a rare condition characterized by the growth of multiple, painful, lipomas benign, fatty tumors. It exists as a separate entity that must be distinguished from other causes of knee pain. Full text full text is available as a scanned copy of the original print version. Adiposis dolorosa dercums disease is a rare, sporadic disease characterised by generalised obesity with pronounced pain in the adipose tissue. For immediate, free, and confidential assistance, download or. Apr 06, 2018 dercums disease or adiposis dolorosa is a chronic as well as progressive condition in which benign tumors of lipids called lipomas develop in the torso and the extremities that lie close to the torso of the body.
Chronic pain is the cardinal symptom and is characterized as aching burning and stabbing. Get a printable copy pdf file of the complete article 937k, or click on a page image below to browse page by page. Adiposis dolorosa genetic and rare diseases information center. It is classified under rare diseases by the national organization for rare disorder nord. Her clinical history and histopathologic data suggested adiposis dolorosa dercums disease. For language access assistance, contact the ncats public information officer. Im posting here out of concern for one of my family members.
Sep 20, 2015 talk to your vso, the depression should be secondary to the pain of the adiposis dolorosa. Dercum disease medigoo health tests and free medical. Mastalgia is generally classified as cyclic, noncyclic, or extramammary. Fariya rasheed department of dermatology, apollo hospital, hyderabad, india. This was preceded by a case report by dercum2 in 1888, and one by henry in 1891. Article on dercums disease imaging mriultrasound update. The site of the presystolic activation and delayed conduction along the reentrant circuit have been shown to have significant abnormalities such as fibrosis, adiposis, and degeneration of the myocardium. This page lists the people with confirmed diagnosis of dercums disease, also known as adiposis dolorosa. The main symptoms of dercums disease, according to the early reports, are obesity and painful adipose tissue. These are maureens notes on possible infectious causes.
Case of adiposis dolorosa dercums disease sage journals. Ideal sources for wikipedias health content are defined in the guideline wikipedia. These adiposes are etiologically divisible into two types. If you try and claim them as due to the gulf war under section 3. However, although it is 20 times more common in women, 16 percent of the reported. All structured data from the file and property namespaces is available under the creative commons cc0 license. Alternative treatments for dercums disease aka adiposis. Adiposis dolorosa was first described in 1892, by dercum, who named the disease adiposis dolorosa to describe the painful adiposities fat accumulations seen in his 3 patients.
Review of dercums disease and proposal of diagnostic. Adiposis dolorosa medigoo health tests and free medical. Adiposis dolorosa is a rare condition characterized by the growth of multiple. In the united states, a rare disease is generally considered to be a disease that affects fewer than 200,000 people. Adiposis dolorosa or dercums disease is an extremely rare disease with characteristic painful lipomas. The imaging features at mri and ultrasound of cases of adiposis dolorosa nine female, four male. Dercums disease articleslinks part i dercums disease. This means that adiposis dolorosa, or a subtype of adiposis dolorosa, affects less than 200,000 people in the us population. Greenbaum, md, john varga, md \sb\longterm treatment with high doses of corticosteroids leads to the development of truncal obesity and focal fatty deposition. Pdf a 46yearold female, known case of adiposis dolorosa since adolescence, noticed painful thickening of scalp in bilateral parietooccipital areas. Dercums disease nord national organization for rare disorders. Dercums disease as a cause of weight loss failure after.